Tretinoin in Korea: Can You Buy It Over the Counter? What a Seoul Pharmacist Sells Instead

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🧴 Seoul Pharmacy Guide · Acne & retinoids

Looking for tretinoin in Korea? Here is the short answer from a pharmacist in Gangnam: you can’t buy it over the counter. Tretinoin cream (Stieva-A) is a prescription-only medicine in Korea, and so is adapalene (Differin, Epiduo).

You may have read online that a Korean pharmacy gel called “Aclean” contains tretinoin. It doesn’t — its active ingredient is salicylic acid. Below is what Korean drug labels actually say, what you can buy without a prescription, and how to get tretinoin legally if you really need it.

PHARMACIST’S SUMMARY
Tretinoin in Korea — quick answer
Over the counter?
No. Tretinoin (Stieva-A) and adapalene (Differin, Epiduo) are prescription-only in Korea
Aclean Gel?
Not tretinoin. It’s 2% salicylic acid, an over-the-counter acne gel (20 g ₩13,000 at Byeolha)
Buy instead
Azelaic acid 20% cream (Azalea, Azelclean) — over the counter, approved for acne
Need tretinoin?
See a dermatology clinic (피부과), then fill the prescription at any pharmacy
Bringing your own
Allowed for personal use in limited amounts — keep it in its original box with your prescription
Not in pregnancy
The Korean labels for tretinoin and adapalene say do not use if pregnant or possibly pregnant
Close-up of acne on the cheek — tretinoin in Korea is prescription only
Acne is the most common reason visitors look for tretinoin in Korea. Photo: Hanna Pad / Pexels

1. Is tretinoin over the counter in Korea?

No. In Korea every topical retinoid medicine is classed as a prescription medicine (전문의약품). A pharmacist can’t sell it to you without a doctor’s prescription, even if you show a prescription from home.

Tretinoin in Korea is prescription only; azelaic acid cream and salicylic acid gel are over the counter
  • Stieva-A cream (tretinoin 0.01%, 0.025%, 0.05%): prescription only. Approved in Korea for acne and for photoaging (fine lines, pigmentation, rough skin) — MFDS label
  • Differin gel/cream (adapalene 0.1%): prescription only, for acne in people 12 and older — MFDS label
  • Epiduo gel (adapalene + benzoyl peroxide): prescription only — MFDS label

This surprises many visitors, because adapalene is sold over the counter in the US. Korea draws the line differently: retinoid medicines stay behind the counter.

2. “Aclean Gel contains tretinoin” — it doesn’t

Several shopping blogs and social media posts describe Aclean Gel (애크린겔) by Dong-A Pharm as a tretinoin-and-clindamycin cream you can buy in any Korean pharmacy. That is not what the Korean drug approval says.

Aclean Gel (애크린겔) by Dong-A Pharm, a 2% salicylic acid acne gel sold over the counter in Korea — not tretinoin
Aclean Gel (애크린겔) — 2% salicylic acid, 20 g. Image: Dong-A Pharm
What the MFDS record actually shows
  • Active ingredient: salicylic acid 20 mg per gram (2%) — no tretinoin, no antibiotic
  • Status: over-the-counter medicine, approved in 2022 for acne
  • How to use: twice a day, morning and evening; start once a day because it can dry the skin
  • Don’t use: around the eyes or on mucous membranes, or on infected or irritated skin; not if you have diabetes or poor circulation

Source: MFDS label for Aclean Gel (item 202204171), checked October 2026.

3. What you can buy without a prescription

If you came to Korea hoping for tretinoin for acne, these are the realistic over-the-counter options at a Korean pharmacy.

Woman checking a pimple in a mirror — over-the-counter acne care at a Korean pharmacy
Mild to moderate acne can often be managed with over-the-counter creams. Photo: Hanna Pad / Pexels

Azelaic acid 20% cream — the closest thing to a “pharmacy acne cream”

  • Azalea Cream (LEO Pharma, 30 g) and Azelclean Cream (Hanmi, 20 g) both contain azelaic acid 20% and are approved in Korea for acne vulgaris — Azalea label · Azelclean label
  • How to use: wash and dry the skin, then apply twice a day (morning and evening). If it stings a lot, cut back to once a day
  • When to expect results: the label says visible improvement usually starts after about 4 weeks
  • At Byeolha Pharmacy: Azalea 30 g ₩29,000 · Azelclean 20 g ₩20,000

Azelaic acid is not a retinoid and won’t do everything tretinoin does — it isn’t approved for wrinkles in Korea, for example. But for everyday acne it’s the strongest option you can pick up without seeing a doctor.

Salicylic acid gel

Aclean Gel (2% salicylic acid) is useful for clogged pores and small breakouts. Don’t layer it on top of tretinoin: the tretinoin label lists salicylic acid among products to be careful combining with.

  • At Byeolha Pharmacy: Aclean Gel 20 g ₩13,000

Retinol skincare

Retinol serums and creams are everywhere in Korean pharmacies and Olive Young, but they’re cosmetics, not medicines. They’re gentler and slower than prescription tretinoin. Fine for maintenance; not a substitute if your dermatologist prescribed tretinoin at home.

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4. How to get a tretinoin prescription in Seoul

Dermatologist examining a patient — getting a tretinoin prescription in Seoul
A dermatology clinic (피부과) visit is the way to get tretinoin in Korea. Photo: Gustavo Fring / Pexels
  1. Find a dermatology clinic. Look for “피부과” — Seoul has many, and areas like Gangnam and Sinnonhyeon are full of them. Many have staff who speak some English.
  2. Bring your passport and, if you have it, your prescription or the product box from home so the doctor can see the strength you use.
  3. See the doctor. Visitors without Korean health insurance pay the full consultation fee, which varies by clinic. Ask the price at reception first.
  4. Take the paper prescription to any pharmacy. Clinics in Korea usually don’t hand out medicine themselves; you fill the prescription at a pharmacy nearby.

Ask the doctor whether the prescribed product is cream or gel and which strength — Korean pharmacies stock what the clinic prescribes, so it’s worth confirming before you leave.

5. Using tretinoin safely: what the Korean label says

Applying acne cream to the cheek — using tretinoin safely
The Korean label: apply at bedtime, and protect your skin from strong sun. Photo: Hanna Pad / Pexels
From the Stieva-A (tretinoin) label
  • How often: once a day at bedtime (or twice). For sensitive skin, once a day or every other day
  • Expect some redness: mild redness and peeling in the first 1–5 weeks is common. If irritation is strong, space out applications
  • Sun: avoid strong sun and sunlamps; use broad-spectrum sunscreen and protective clothing
  • Benzoyl peroxide: don’t apply at the same time — the label suggests using one in the morning and the other at night
  • Pregnancy: do not use if you are or may be pregnant, or while breastfeeding
  • Don’t use on: sunburned, eczema-affected, cut or scraped skin, or with acute dermatitis or rosacea

Travel itself can make retinoid skin more sensitive: the label notes that wind, cold and low humidity can increase dryness and irritation. If your skin is raw from a long flight, give it a night or two before restarting.

6. Bringing your own tretinoin to Korea

If you already use tretinoin, the simplest option is to bring it. The U.S. Embassy in Korea notes that for non-controlled medicines you may bring up to six bottles or a three-month supply for personal use — U.S. Embassy Seoul.

  • Keep it in its original packaging with the label showing your name if possible
  • Carry a copy of your prescription or a doctor’s note, especially for larger amounts
  • Don’t plan to buy a refill here without a Korean prescription — the pharmacy can’t sell it to you
💊
Byeolha Pharmacy near Sinnonhyeon Station in Gangnam, an English-speaking Korean pharmacy for acne creams without a prescription WHERE THIS IS WRITTEN FROM

Byeolha Pharmacy 별하약국

📍 1 minute from Sinnonhyeon Station Exit 3 (Line 9 · Shinbundang Line), Gangnam, Seoul

LANGUAGES
English · 日本語 · 中文
한국어
HOURS
Mon–Fri 9:30–21:00
Sat 9:00–18:00
PAYMENT
Apple Pay · Alipay
WeChat · Tax refund

7. Tretinoin in Korea FAQ

Q1. Can you buy tretinoin over the counter in Korea?
No. Tretinoin cream (Stieva-A) is a prescription-only medicine in Korea. You need a prescription from a Korean doctor, usually a dermatology clinic, and then any pharmacy can fill it.
Q2. Does Aclean Gel contain tretinoin?
No. According to its Korean drug approval, Aclean Gel by Dong-A Pharm contains 2% salicylic acid. It’s an over-the-counter acne gel with no tretinoin and no antibiotic. At Byeolha Pharmacy a 20 g tube is ₩13,000.
Q3. Is adapalene (Differin) over the counter in Korea?
No. Unlike in the US, Differin (adapalene) and Epiduo (adapalene with benzoyl peroxide) are prescription-only medicines in Korea.
Q4. What is the best over-the-counter alternative to tretinoin in Korea?
For acne, azelaic acid 20% cream (Azalea or Azelclean) is the strongest over-the-counter option. It’s approved in Korea for acne and is used twice a day. It isn’t a retinoid, so it won’t replace tretinoin for wrinkles.
Q5. Can a Korean pharmacy fill my prescription from home?
No. Korean pharmacies can only dispense prescription medicines on a prescription written by a doctor in Korea. See a local clinic for a new prescription.
Q6. Can I bring tretinoin into Korea?
Yes, for personal use in limited amounts. The U.S. Embassy in Korea says non-controlled medicines can be brought in up to six bottles or a three-month supply. Keep it in the original packaging with your prescription.
Q7. Can I use tretinoin while pregnant?
No. The Korean label for tretinoin cream says not to use it if you are or may be pregnant, or while breastfeeding. The adapalene label says the same. Talk to your doctor about alternatives.
Lee Jeong-hoon, licensed pharmacist at Byeolha Pharmacy in Gangnam, Seoul

About the author

Lee Jeong-hoon · Licensed pharmacist · Byeolha Pharmacy, Gangnam

Lee Jeong-hoon is a licensed pharmacist (15 years, Korean license no. 61641). He worked in pharmaceutical R&D and regulatory affairs at a multinational drug company before opening Byeolha Pharmacy in Gangnam, which he has run for seven years.

He writes these guides from the official Korean drug labels, so visitors get the same information a Korean pharmacist works from.

This guide is for general information and does not replace advice from a doctor or pharmacist. Prices are Byeolha Pharmacy prices as of October 2026 and may differ elsewhere.
© 2026 DrugThru

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